Combining Ecstasy with other drugs
Amphetamine. Many party users like to take Ecstasy with half a gram of speed which adds excitement, while others use speed to dab onto their gums to keep up energy through the night and prolong the experience at relatively low cost.
LSD and Mushrooms. Some ravers prefer to combine E with
LSD (known as candy-flip in the USA) or with psilocybin mushrooms, thus
combining hallucinogenic qualities to the warmth of Ecstasy. This also extends
the experience at low cost, as LSD lasts for about twice as long as MDMA.
Home users often use this combination, particularly in natural surroundings.
Ketamine is also sometimes used while on Ecstasy for self exploration.
Virtually no research has been done on dangerous combinations, although it is known that mono amine oxidase inhibitors (MAOIs) should not be used with MDMA. It is also likely that some prescription and over-the-counter drugs may have bad interactions when used with Ecstasy, possibly anti-histamines and cold remedies, while amphetamines and alcohol also tax the liver and the combination of these with Ecstasy may cause a bad reaction even though each can be tolerated on its own.
Prozac (fluoxetine) and other selective serotonin reuptake inhibitors (SSRIs) reduce the effect of Ecstasy in some people, but it is widely used with or just after Ecstasy to prevent neurotoxicity. Animal studies show that SSRIs prevent toxicity, presumed to be due to preventing toxic metabolites from being reabsorbed into these sites.
The Essential Psychedelic Guide is a book that contains a section on
combinations of various drugs, some including MDMA. This can be obtained
through bookshops included in Links to other sites.